CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.120 | 6 Propeller |
|
2.120.10 | Neuraminidase |
|
2.120.10.10 |
Domain Context
CATH Clusters
| Superfamily | 2.120.10.10 |
| Functional Family |
Enzyme Information
| 3.2.1.18 |
Exo-alpha-sialidase.
based on mapping to UniProt Q6XV27
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
-!- The enzyme does not act on 4-O-acetylated sialic acids. -!- An endo-alpha-sialidase activity is listed as EC 3.2.1.129. -!- See also EC 4.2.2.15.
|
UniProtKB Entries (1)
| Q6XV27 |
NRAM_I56A2
Influenza A virus (A/duck/England/1/1956(H11N6))
Neuraminidase
|
PDB Structure
| PDB | 1W20 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Crystal Structure of Type a Influenza Virus Neuraminidase of the N6 Subtype Reveals the Existence of Two Separate Neu5Ac Binding Sites
To be Published
|
