CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family 3-isopropylmalate dehydrogenase

Enzyme Information

1.1.1.85
3-isopropylmalate dehydrogenase.
based on mapping to UniProt P9WKK9
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.

UniProtKB Entries (1)

P9WKK9
LEU3_MYCTU
Mycobacterium tuberculosis H37Rv
3-isopropylmalate dehydrogenase

PDB Structure

PDB 1W0D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The High Resolution Structure of Leub (Rv2995C) from Mycobacterium Tuberculosis
Singh, R.K., Kefala, G., Janowski, R., Mueller-Dieckmann, C., Von Kries, J.P., Weiss, M.S.
J.Mol.Biol.
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