CATH Domain 1vyqA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.40	Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A
	2.70.40.10	Deoxyuridine triphosphatase (dUTPase)

Domain Context

CATH Clusters

Superfamily	2.70.40.10
Functional Family	dUTP pyrophosphatase

Enzyme Information

UniProtKB Entries (1)

Q8II92_PLAF7

Plasmodium falciparum 3D7

Deoxyuridine 5'-triphosphate nucleotidohydrolase

PDB Structure

PDB	1VYQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Dutpase as a Platform for Antimalarial Drug Design: Structural Basis for the Selectivity of a Class of Nucleoside Inhibitors. Whittingham, J.L., Leal, I., Nguyen, C., Kasinathan, G., Bell, E., Jones, A.F., Berry, C., Benito, A., Turkenburg, J.P., Dodson, E.J., Ruiz Perez, L.M., Wilkinson, A.J., Johansson, N.G., Brun, R., Gilbert, I.H., Gonzalez Pacanowska, D., Wilson, K.S. Structure