CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.580 | Pseudouridine synthase I, catalytic domain, N-terminal subdomain |
Domain Context
CATH Clusters
| Superfamily | Pseudouridine synthase I, catalytic domain, N-terminal subdomain |
| Functional Family |
Enzyme Information
| 5.4.99.12 |
tRNA pseudouridine(38-40) synthase.
based on mapping to UniProt Q5SHU9
tRNA uridine(38-40) = tRNA pseudouridine(38-40).
-!- The uridylate residues at positions 38, 39 and 40 of nearly all tRNAs are isomerized to pseudouridine. -!- TruA specifically modifies uridines at positions 38, 39, and/or 40 in the anticodon stem loop of tRNAs with highly divergent sequences and structures.
|
UniProtKB Entries (1)
| Q5SHU9 |
TRUA_THET8
Thermus thermophilus HB8
TRNA pseudouridine synthase A
|
PDB Structure
| PDB | 1VS3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of tRNA pseudouridine synthase TruA from Thermus thermophilus HB8.
Rna Biol.
|
