CATH Domain 1vquA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1030	Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2
	3.40.1030.10	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain

Domain Context

CATH Clusters

Superfamily	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
Functional Family	Anthranilate phosphoribosyltransferase

Enzyme Information

2.4.2.18

Anthranilate phosphoribosyltransferase.

based on mapping to UniProt Q8YXQ9

N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.

-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).

UniProtKB Entries (1)

Q8YXQ9

TRPD2_NOSS1

Nostoc sp. PCC 7120

Anthranilate phosphoribosyltransferase 2

PDB Structure

PDB	1VQU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of Anthranilate phosphoribosyltransferase 2 (17130499) from Nostoc sp. at 1.85 A resolution Joint Center for Structural Genomics (JCSG) To be published