CATH Classification

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family transcription initiation factor IIB

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q00403
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (2)

Q00403
TF2B_HUMAN
Homo sapiens
Transcription initiation factor IIB
P28147
TBP1_ARATH
Arabidopsis thaliana
TATA-box-binding protein 1

PDB Structure

PDB 1VOL
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a TFIIB-TBP-TATA-element ternary complex.
Nikolov, D.B., Chen, H., Halay, E.D., Usheva, A.A., Hisatake, K., Lee, D.K., Roeder, R.G., Burley, S.K.
Nature
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