CATH Domain 1vlqA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1820	alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily	alpha/beta hydrolase
Functional Family	Cephalosporin-C deacetylase

Enzyme Information

3.1.1.72	Acetylxylan esterase. based on mapping to UniProt Q9WXT2 Deacetylation of xylans and xylo-oligosaccharides. -!- Catalyzes the hydrolysis of acetyl groups from polymeric xylan, acetylated xylose, acetylated glucose, alpha-napthyl acetate, p-nitrophenyl acetate but not from triacetylglycerol. -!- Does not act on acetylated mannan or pectin.
3.1.1.41	Cephalosporin-C deacetylase. based on mapping to UniProt Q9WXT2 Cephalosporin C + H(2)O = deacetylcephalosporin C + acetate. -!- Hydrolyzes the acetyl ester bond on the 10-position of the antibiotic cephalosporin C.

UniProtKB Entries (1)

CAH_THEMA

Thermotoga maritima MSB8

Cephalosporin-C deacetylase

PDB Structure

PDB	1VLQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima. Levisson, M., Han, G.W., Deller, M.C., Xu, Q., Biely, P., Hendriks, S., Ten Eyck, L.F., Flensburg, C., Roversi, P., Miller, M.D., McMullan, D., von Delft, F., Kreusch, A., Deacon, A.M., van der Oost, J., Lesley, S.A., Elsliger, M.A., Kengen, S.W., Wilson, I.A. Proteins