CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.42.10
Functional Family Tyrosine-protein phosphatase non-receptor type 13

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q64512
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q61315
APC_MOUSE
Mus musculus
Adenomatous polyposis coli protein

PDB Structure

PDB 1VJ6
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering.
Gianni, S., Walma, T., Arcovito, A., Calosci, N., Bellelli, A., Engstrom, A., Travaglini-Allocatelli, C., Brunori, M., Jemth, P., Vuister, G.W.
Structure
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