CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.79 | Nucleoside Triphosphate Pyrophosphohydrolase |
|
3.90.79.10 | Nucleoside Triphosphate Pyrophosphohydrolase |
Domain Context
CATH Clusters
| Superfamily | Nucleoside Triphosphate Pyrophosphohydrolase |
| Functional Family | Diadenosine hexaphosphate hydrolase |
Enzyme Information
| 3.6.1.61 |
Diadenosine hexaphosphate hydrolase (ATP-forming).
based on mapping to UniProt Q75UV1
(1) P(1),P(6)-bis(5'-adenosyl)hexaphosphate + H(2)O = 2 ATP. (2) P(1),P(5)-bis(5'-adenosyl)pentaphosphate + H(2)O = ATP + ADP. (3) P(1),P(4)-bis(5'-adenosyl)tetraphosphate + H(2)O = ATP + AMP.
-!- The enzyme hydrolyzes P(1),P(4)-bis(5-guanosyl) tetraphosphate very slowly (cf. EC 3.6.1.17).
|
UniProtKB Entries (1)
| Q75UV1 |
NDX1_THETH
Thermus thermophilus
Diadenosine hexaphosphate hydrolase
|
PDB Structure
| PDB | 1VCD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of Nudix Protein Ndx1 from Thermus thermophilus HB8 in binary complex with diadenosine hexaphosphate
To be Published
|