CATH Classification

Domain Context

CATH Clusters

Superfamily Pseudouridine synthase
Functional Family Pseudouridine synthase

Enzyme Information

5.4.99.24
23S rRNA pseudouridine(955/2504/2580) synthase.
based on mapping to UniProt P0AA39
23S rRNA uridine(955)/uridine(2504)/uridine(2580) = 23S rRNA pseudouridine(955)/pseudouridine(2504)/pseudouridine(2580).
-!- The enzyme converts uridines at position 955, 2504 and 2580 of 23S rRNA to pseudouridines.

UniProtKB Entries (1)

P0AA39
RLUC_ECOLI
Escherichia coli K-12
Ribosomal large subunit pseudouridine synthase C

PDB Structure

PDB 1V9K
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of the catalytic domains of pseudouridine synthases RluC and RluD from Escherichia coli
Mizutani, K., Machida, Y., Unzai, S., Park, S.-Y., Tame, J.R.H.
Biochemistry