CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.1400 | Aminomethyltransferase beta-barrel domains |
Domain Context
CATH Clusters
| Superfamily | Aminomethyltransferase beta-barrel domains |
| Functional Family |
Enzyme Information
| 2.1.2.10 |
Aminomethyltransferase.
based on mapping to UniProt O58888
[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH(3).
-!- A component, with EC 1.4.4.2 and EC 1.8.1.4, of the glycine cleavage system, formerly known as glycine synthase. -!- The glycine cleavage system is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein.
|
UniProtKB Entries (1)
| O58888 |
GCST_PYRHO
Pyrococcus horikoshii OT3
Probable aminomethyltransferase
|
PDB Structure
| PDB | 1V5V |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of a component of glycine cleavage system: T-protein from Pyrococcus horikoshii OT3 at 1.5 A resolution
Proteins
|
