CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome c oxidase-like, subunit I domain
Functional Family Cytochrome c oxidase subunit 1

Enzyme Information

1.9.3.1
Cytochrome-c oxidase.
based on mapping to UniProt P00396
4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.
-!- The reduction of O(2) to water is accompanied by the extrusion of four protons from the intramitochondrial compartment. -!- Several bacteria appear to contain analogous oxidases.

UniProtKB Entries (1)

P10175
COX8B_BOVIN
Bos taurus
Cytochrome c oxidase subunit 8B, mitochondrial

PDB Structure

PDB 1V54
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process.
Tsukihara, T., Shimokata, K., Katayama, Y., Shimada, H., Muramoto, K., Aoyama, H., Mochizuki, M., Shinzawa-Itoh, K., Yamashita, E., Yao, M., Ishimura, Y., Yoshikawa, S.
Proc.Natl.Acad.Sci.Usa