1 keywords

CATH Domain 1up6A02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.110 L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
Homologous Superfamily 3.90.110.10 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family

Enzyme Information

3.2.1.86
6-phospho-beta-glucosidase.
based on mapping to UniProt Q9X108
6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H(2)O = D-glucose + D-glucose 6-phosphate.
-!- Also hydrolyzes several other phospho-beta-D-glucosides, but not their non-phosphorylated forms.

UniProtKB Entries (1)

Q9X108
BGLT_THEMA
Thermotoga maritima MSB8
6-phospho-beta-glucosidase BglT

PDB Structure

PDB 1UP6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An Unusual Mechanism of Glycoside Hydrolysis Involving Redox and Elimination Steps by a Family 4 Beta-Glycosidase from Thermotoga Maritima.
Yip, V.L., Varrot, A., Davies, G.J., Rajan, S.S., Yang, X., Thompson, J., Anderson, W.F., Withers, S.G.
J.Am.Chem.Soc.