CATH Domain 1uouA02

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1030	Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2
	3.40.1030.10	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain

Superfamily	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
Functional Family	Pyrimidine-nucleoside phosphorylase

2.4.2.4

Thymidine phosphorylase.

based on mapping to UniProt P19971

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.

-!- In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6. -!- Formerly EC 2.4.2.23.

TYPH_HUMAN

Homo sapiens

Thymidine phosphorylase

PDB	1UOU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of Human Thymidine Phosphorylase in Complex with a Small Molecule Inhibitor Norman, R.A., Barry, S.T., Bate, M., Breed, J., Colls, J.G., Ernill, R.J., Luke, R.W.A., Minshull, C.A., Mcalister, M.S.B., Mccall, E.J., Mcmicken, H.H.J., Paterson, D.S., Timms, D., Tucker, J.A., Pauptit, R.A. Structure