CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.740 | Isoleucyl-tRNA Synthetase; domain 2 |
|
3.90.740.10 | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain |
Domain Context
CATH Clusters
| Superfamily | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain |
| Functional Family |
Enzyme Information
| 6.1.1.5 |
Isoleucine--tRNA ligase.
based on mapping to UniProt P56690
ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile).
|
UniProtKB Entries (1)
| P56690 |
SYI_THET8
Thermus thermophilus HB8
Isoleucine--tRNA ligase
|
PDB Structure
| PDB | 1UE0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine.
J.Biol.Chem.
|
