CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.110 | Butyryl-CoA Dehydrogenase, subunit A; domain 2 | |
2.40.110.10 | Butyryl-CoA Dehydrogenase, subunit A, domain 2 |
Domain Context
CATH Clusters
Superfamily | Butyryl-CoA Dehydrogenase, subunit A, domain 2 |
Functional Family | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial |
Enzyme Information
1.3.8.7 |
Medium-chain acyl-CoA dehydrogenase.
based on mapping to UniProt P41367
A medium-chain acyl-CoA + electron-transfer flavoprotein = a medium-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein.
-!- One of several enzymes that catalyze the first step in fatty acids beta-oxidation. -!- The enzyme from pig liver can accept substrates with acyl chain lengths of 4 to 16 carbon atoms, but is most active with C(8) to C(12) compounds. -!- The enzyme from rat does not accept C(16) at all and is most active with C(6)-C(8) compounds. -!- cf. EC 1.3.8.1, EC 1.3.8.8 and EC 1.3.8.9. -!- Formerly EC 1.3.2.2 and EC 1.3.99.3.
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UniProtKB Entries (1)
P41367 |
ACADM_PIG
Sus scrofa
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
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PDB Structure
PDB | 1UDY |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of the transition state analog of medium-chain acyl-CoA dehydrogenase. Crystallographic and molecular orbital studies on the charge-transfer complex of medium-chain acyl-CoA dehydrogenase with 3-thiaoctanoyl-CoA
J.BIOCHEM.(TOKYO)
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