CATH Classification

Domain Context

CATH Clusters

Superfamily Farnesyl Diphosphate Synthase
Functional Family Farnesyl pyrophosphate synthase

Enzyme Information

2.5.1.10
(2E,6E)-farnesyl diphosphate synthase.
based on mapping to UniProt P08836
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)- farnesyl diphosphate.
-!- Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate. -!- The enzyme will not accept larger prenyl diphosphates as efficient donors.
2.5.1.1
Dimethylallyltranstransferase.
based on mapping to UniProt P08836
Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
-!- Will not accept larger prenyl diphosphates as efficient donors.

UniProtKB Entries (1)

P08836
FPPS_CHICK
Gallus gallus
Farnesyl pyrophosphate synthase

PDB Structure

PDB 1UBW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Regulation of product chain length by isoprenyl diphosphate synthases.
Tarshis, L.C., Proteau, P.J., Kellogg, B.A., Sacchettini, J.C., Poulter, C.D.
Proc.Natl.Acad.Sci.USA
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