CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1110 | Adenosine kinase, small domain |
|
3.30.1110.20 |
Domain Context
CATH Clusters
| Superfamily | 3.30.1110.20 |
| Functional Family |
Enzyme Information
| 2.7.1.147 |
ADP-specific glucokinase.
based on mapping to UniProt Q9V2Z6
ADP + D-glucose = AMP + D-glucose 6-phosphate.
-!- The enzyme from Pyrococcus furiosus is highly specific for D-glucose; there is some activity with 2-deoxy-D-glucose, but no activity with D-fructose, D-mannose or D-galactose as the substrate. -!- No activity is detected when ADP is replaced by ATP, GDP, phosphoenolpyruvate, diphosphate or polyphosphate.
|
UniProtKB Entries (1)
| Q9V2Z6 |
GLKA_PYRFU
Pyrococcus furiosus DSM 3638
ADP-dependent glucokinase
|
PDB Structure
| PDB | 1UA4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of an ADP-dependent glucokinase from Pyrococcus furiosus: implications for a sugar-induced conformational change in ADP-dependent kinase
J.Mol.Biol.
|