CATH Classification

Domain Context

CATH Clusters

Superfamily Inositol polyphosphate kinase
Functional Family Kinase

Enzyme Information

2.7.1.127
Inositol-trisphosphate 3-kinase.
based on mapping to UniProt P17105
ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate.

UniProtKB Entries (1)

P17105
IP3KA_RAT
Rattus norvegicus
Inositol-trisphosphate 3-kinase A

PDB Structure

PDB 1TZD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the catalytic core of inositol 1,4,5-trisphosphate 3-kinase
Miller, G.J., Hurley, J.H.
Mol.Cell