CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.20 | Ubiquitin-like (UB roll) |
|
3.10.20.260 | NEDD8-activating enzyme E1, catalytic subunit |
Domain Context
CATH Clusters
| Superfamily | NEDD8-activating enzyme E1, catalytic subunit |
| Functional Family |
Enzyme Information
| 6.2.1.- |
Acid--thiol ligases.
based on mapping to UniProt Q8TBC4
|
UniProtKB Entries (1)
| Q8TBC4 |
UBA3_HUMAN
Homo sapiens
NEDD8-activating enzyme E1 catalytic subunit
|
PDB Structure
| PDB | 1TT5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.
Nat.Struct.Mol.Biol.
|
