CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Triosephosphate isomerase |
Enzyme Information
| 4.2.3.3 |
Methylglyoxal synthase.
based on mapping to UniProt P00940
Glycerone phosphate = methylglyoxal + phosphate.
-!- Does not act on D-glyceraldehyde 3-phosphate. -!- Formerly EC 4.2.99.11.
|
| 5.3.1.1 |
Triose-phosphate isomerase.
based on mapping to UniProt P00940
D-glyceraldehyde 3-phosphate = glycerone phosphate.
|
UniProtKB Entries (1)
| P00940 |
TPIS_CHICK
Gallus gallus
Triosephosphate isomerase
|
PDB Structure
| PDB | 1TPC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules.
Biochemistry
|
