CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.870 | DHBP synthase |
|
3.90.870.10 | DHBP synthase |
Domain Context
CATH Clusters
| Superfamily | DHBP synthase |
| Functional Family | 3,4-dihydroxy-2-butanone 4-phosphate synthase |
Enzyme Information
| 4.1.99.12 |
3,4-dihydroxy-2-butanone-4-phosphate synthase.
based on mapping to UniProt Q5A3V6
D-ribulose 5-phosphate = formate + L-3,4-dihydroxybutan-2-one 4-phosphate.
-!- The reaction involves an intramolecular skeletal rearrangement, with the bonds in D-ribulose 5-phosphate that connect C-3 and C-5 to C-4 being broken, C-4 being removed as formate and reconnection of C-3 and C-5. -!- The phosphorylated four-carbon product (L-3,4-dihydroxybutan-2-one 4-phosphate) is an intermediate in the biosynthesis of riboflavin.
|
UniProtKB Entries (1)
| Q5A3V6 |
RIB3_CANAL
Candida albicans SC5314
3,4-dihydroxy-2-butanone 4-phosphate synthase
|
PDB Structure
| PDB | 1TKS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans.
J.Mol.Biol.
|