CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Titin a

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q8WZ42
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q8WZ42
TITIN_HUMAN
Homo sapiens
Titin

PDB Structure

PDB 1TKI
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
Structural basis for activation of the titin kinase domain during myofibrillogenesis.
Mayans, O., van der Ven, P.F., Wilm, M., Mues, A., Young, P., Furst, D.O., Wilmanns, M., Gautel, M.
Nature
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