CATH Classification

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family transcription initiation factor IIB

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q00403
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

Q00403
TF2B_HUMAN
Homo sapiens
Transcription initiation factor IIB

PDB Structure

PDB 1TFB
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Human general transcription factor TFIIB: conformational variability and interaction with VP16 activation domain.
Hayashi, F., Ishima, R., Liu, D., Tong, K.I., Kim, S., Reinberg, D., Bagby, S., Ikura, M.
Biochemistry
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