CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.410 | Factor Xa Inhibitor |
|
4.10.410.10 | Pancreatic trypsin inhibitor Kunitz domain |
Domain Context
CATH Clusters
| Superfamily | Pancreatic trypsin inhibitor Kunitz domain |
| Functional Family | Amyloid beta A4 protein |
Enzyme Information
UniProtKB Entries (2)
| P00760 |
TRY1_BOVIN
Bos taurus
Cationic trypsin
|
| P05067 |
A4_HUMAN
Homo sapiens
Amyloid-beta precursor protein
|
PDB Structure
| PDB | 1TAW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Protein Sci.
|