CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.420 | Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain |
Domain Context
CATH Clusters
| Superfamily | Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain |
| Functional Family |
Enzyme Information
| 1.1.1.88 |
Hydroxymethylglutaryl-CoA reductase.
based on mapping to UniProt P13702
(R)-mevalonate + CoA + 2 NAD(+) = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.
|
UniProtKB Entries (1)
| P13702 |
MVAA_PSEMV
Pseudomonas mevalonii
3-hydroxy-3-methylglutaryl-coenzyme A reductase
|
PDB Structure
| PDB | 1T02 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase.
J.Biol.Chem.
|
