1 keywords

CATH Domain 1sy6A02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family T-cell surface glycoprotein CD3 epsilon chain

Enzyme Information

UniProtKB Entries (2)

Q6PJA7
Q6PJA7_MOUSE
Mus musculus
Igh protein
P09693
CD3G_HUMAN
Homo sapiens
T-cell surface glycoprotein CD3 gamma chain

PDB Structure

PDB 1SY6
External Links
Method X-RAY DIFFRACTION
Organism Mus
Primary Citation
Crystal structure of the human T cell receptor CD3(epsilon)(gamma) heterodimer complexed to the therapeutic mAb OKT3.
Kjer-Nielsen, L., Dunstone, M.A., Kostenko, L., Ely, L.K., Beddoe, T., Mifsud, N.A., Purcell, A.W., Brooks, A.G., McCluskey, J., Rossjohn, J.
Proc.Natl.Acad.Sci.USA