CATH Domain 1sooA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.300	Adenylosuccinate Synthetase, subunit A; domain 2
	1.10.300.10	Adenylosuccinate Synthetase, subunit A, domain 2

Domain Context

CATH Clusters

Superfamily	Adenylosuccinate Synthetase, subunit A, domain 2
Functional Family	Adenylosuccinate synthetase

Enzyme Information

6.3.4.4

Adenylosuccinate synthase.

based on mapping to UniProt P0A7D4

GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)- AMP.

UniProtKB Entries (1)

PURA_ECOLI

Escherichia coli K-12

Adenylosuccinate synthetase

PDB Structure

PDB	1SOO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The mode of action and the structure of a herbicide in complex with its target: binding of activated hydantocidin to the feedback regulation site of adenylosuccinate synthetase. Fonne-Pfister, R., Chemla, P., Ward, E., Girardet, M., Kreuz, K.E., Honzatko, R.B., Fromm, H.J., Schar, H.P., Grutter, M.G., Cowan-Jacob, S.W. Proc.Natl.Acad.Sci.USA