CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.140 | Butyryl-CoA Dehydrogenase, subunit A; domain 3 |
|
1.20.140.60 |
Domain Context
CATH Clusters
| Superfamily | 1.20.140.60 |
| Functional Family | Calmodulin-sensitive adenylate cyclase |
Enzyme Information
| 4.6.1.1 |
Adenylate cyclase.
based on mapping to UniProt P40136
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.
|
UniProtKB Entries (2)
| P40136 |
CYAA_BACAN
Bacillus anthracis
Calmodulin-sensitive adenylate cyclase
|
| P0DP25 |
CALM3_HUMAN
Homo sapiens
Calmodulin-3
|
PDB Structure
| PDB | 1SK6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate.
J.Biol.Chem.
|
