CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.40 | Serine-tRNA synthetase, tRNA binding domain |
Domain Context
CATH Clusters
| Superfamily | Serine-tRNA synthetase, tRNA binding domain |
| Functional Family |
Enzyme Information
| 6.1.1.11 |
Serine--tRNA ligase.
based on mapping to UniProt P34945
(1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec).
-!- This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1.
|
UniProtKB Entries (1)
| P34945 |
SYS_THET2
Thermus thermophilus HB27
Serine--tRNA ligase
|
PDB Structure
| PDB | 1SES |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.
Science
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