CATH Classification

Domain Context

CATH Clusters

Superfamily Metalloproteases ("zincins"), catalytic domain like
Functional Family Botulinum neurotoxin type B

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P10844
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P10844
BXB_CLOBO
Clostridium botulinum
Botulinum neurotoxin type B

PDB Structure

PDB 1S0E
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Role of metals in the biological activity of Clostridium botulinum neurotoxins
Eswaramoorthy, S., Kumaran, D., Keller, J., Swaminathan, S.
Biochemistry
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