CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase |
Enzyme Information
| 2.6.1.62 |
Adenosylmethionine--8-amino-7-oxononanoate transaminase.
based on mapping to UniProt P12995
S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4- methylthio-2-oxobutanoate + 7,8-diaminononanoate.
-!- S-adenosylhomocysteine can also act as donor.
|
UniProtKB Entries (1)
| P12995 |
BIOA_ECOLI
Escherichia coli K-12
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
|
PDB Structure
| PDB | 1S06 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry
|
