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1 keywords

CATH Domain 1rpiB00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q9QM22
Q9QM22_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 1RPI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of a multidrug-resistant human immunodeficiency virus type 1 protease reveal an expanded active-site cavity.
Logsdon, B.C., Vickrey, J.F., Martin, P., Proteasa, G., Koepke, J.I., Terlecky, S.R., Wawrzak, Z., Winters, M.A., Merigan, T.C., Kovari, L.C.
J.Virol.
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