CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.800 | Arginase; Chain A |
|
3.40.800.10 | Ureohydrolase domain |
Domain Context
CATH Clusters
| Superfamily | Ureohydrolase domain |
| Functional Family | Arginase-1 |
Enzyme Information
| 3.5.3.1 |
Arginase.
based on mapping to UniProt P07824
L-arginine + H(2)O = L-ornithine + urea.
-!- Also hydrolyzes alpha-N-substituted L-arginines and canavanine.
|
UniProtKB Entries (1)
| P07824 |
ARGI1_RAT
Rattus norvegicus
Arginase-1
|
PDB Structure
| PDB | 1R1O |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Design of Amino Acid Sulfonamides as Transition-State Analogue Inhibitors of Arginase
J.Am.Chem.Soc.
|
