CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.10 | S15/NS1, RNA-binding |
Domain Context
CATH Clusters
| Superfamily | S15/NS1, RNA-binding |
| Functional Family | bifunctional glutamate/proline--tRNA ligase |
Enzyme Information
| 6.1.1.17 |
Glutamate--tRNA ligase.
based on mapping to UniProt Q7SIA2
ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).
|
| 6.1.1.15 |
Proline--tRNA ligase.
based on mapping to UniProt Q7SIA2
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).
|
UniProtKB Entries (1)
| Q7SIA2 |
SYEP_CRIGR
Cricetulus griseus
Bifunctional glutamate/proline--tRNA ligase
|
PDB Structure
| PDB | 1R1B |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
A recurrent RNA-binding domain is appended to eukaryotic aminoacyl-tRNA synthetases.
EMBO J.
|
