CATH Domain 1qusA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.530	Lysozyme
	1.10.530.10

Domain Context

CATH Clusters

Superfamily	1.10.530.10
Functional Family	Lytic murein transglycosylase B

Enzyme Information

4.2.2.n1

Peptidoglycan lytic exotransglycosylase.

based on mapping to UniProt P41052

Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.

UniProtKB Entries (1)

P41052

MLTB_ECOLI

Escherichia coli K-12

Membrane-bound lytic murein transglycosylase B

PDB Structure

PDB	1QUS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of Escherichia coli lytic transglycosylase Slt35 reveals a lysozyme-like catalytic domain with an EF-hand. van Asselt, E.J., Dijkstra, A.J., Kalk, K.H., Takacs, B., Keck, W., Dijkstra, B.W. Structure Fold.Des.