CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.730 | Isoleucyl-tRNA Synthetase; Domain 1 |
|
1.10.730.10 | Isoleucyl-tRNA Synthetase; Domain 1 |
Domain Context
CATH Clusters
| Superfamily | Isoleucyl-tRNA Synthetase; Domain 1 |
| Functional Family |
Enzyme Information
| 6.1.1.5 |
Isoleucine--tRNA ligase.
based on mapping to UniProt P41972
ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile).
|
UniProtKB Entries (1)
| P41972 |
SYI1_STAAU
Staphylococcus aureus
Isoleucine--tRNA ligase
|
PDB Structure
| PDB | 1QU3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin.
Science
|
