CATH Classification

Domain Context

CATH Clusters

Superfamily PLAT/LH2 domain
Functional Family Phospholipase C

Enzyme Information

3.1.4.3
Phospholipase C.
based on mapping to UniProt Q0TV31
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.
-!- The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol. -!- The enzyme from seminal plasma does not act on phosphatidylinositol.

UniProtKB Entries (1)

Q0TV31
PHLC_CLOP1
Clostridium perfringens ATCC 13124
Phospholipase C

PDB Structure

PDB 1QMD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Characterisation of the Calcium-Binding C-Terminal Domain of Clostridium Perfringens Alpha-Toxin
Naylor, C.E., Jepson, M., Crane, D.T., Titball, R.W., Miller, J., Basak, A.K., Bolgiano, B.
J.Mol.Biol.