CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.2020 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.2020 |
| Functional Family |
Enzyme Information
| 2.4.2.8 |
Hypoxanthine phosphoribosyltransferase.
based on mapping to UniProt Q26997
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- Guanine and 6-mercaptopurine can replace hypoxanthine.
|
| 2.4.2.22 |
Xanthine phosphoribosyltransferase.
based on mapping to UniProt Q26997
XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine.
|
UniProtKB Entries (1)
| Q26997 |
HGXR_TOXGO
Toxoplasma gondii
Hypoxanthine-guanine-xanthine phosphoribosyltransferase
|
PDB Structure
| PDB | 1QK5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Toxoplasma Gondii Hypoxanthine-Guanine Phosphoribosyltransferase with Xmp, Pyrophosphate and Two Mg2+ Ions Bound: Insights Into the Catalytic Mechanism
Biochemistry
|
