CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.420.40
Functional Family Hexokinase 1

Enzyme Information

2.7.1.1
Hexokinase.
based on mapping to UniProt P19367
ATP + D-hexose = ADP + D-hexose 6-phosphate.
-!- D-glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors. -!- ITP and dATP can act as donors.

UniProtKB Entries (1)

P19367
HXK1_HUMAN
Homo sapiens
Hexokinase-1

PDB Structure

PDB 1QHA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control.
Rosano, C., Sabini, E., Rizzi, M., Deriu, D., Murshudov, G., Bianchi, M., Serafini, G., Magnani, M., Bolognesi, M.
Structure Fold.Des.