CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.15 | Metallo-beta-lactamase; Chain A |
|
3.60.15.10 | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
| Functional Family | Hydroxyacylglutathione hydrolase, mitochondrial |
Enzyme Information
| 3.1.2.6 |
Hydroxyacylglutathione hydrolase.
based on mapping to UniProt Q16775
S-(2-hydroxyacyl)glutathione + H(2)O = glutathione + a 2-hydroxy carboxylate.
-!- Also hydrolyzes S-acetoacetylglutathione, more slowly. -!- Formerly EC 3.1.2.8.
|
UniProtKB Entries (1)
| Q16775 |
GLO2_HUMAN
Homo sapiens
Hydroxyacylglutathione hydrolase, mitochondrial
|
PDB Structure
| PDB | 1QH3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des.
|
