CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.230 | Outer membrane phospholipase (ompla); Chain C |
|
2.40.230.10 | Phospholipase A1 |
Domain Context
CATH Clusters
| Superfamily | Phospholipase A1 |
| Functional Family | Phospholipase A(1) |
Enzyme Information
| 3.1.1.4 |
Phospholipase A(2).
based on mapping to UniProt P0A921
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.
|
| 3.1.1.32 |
Phospholipase A(1).
based on mapping to UniProt P0A921
Phosphatidylcholine + H(2)O = 2-acylglycerophosphocholine + a carboxylate.
-!- Has a much broader specificity than EC 3.1.1.4.
|
UniProtKB Entries (1)
| P0A921 |
PA1_ECOLI
Escherichia coli K-12
Phospholipase A1
|
PDB Structure
| PDB | 1QD5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural evidence for dimerization-regulated activation of an integral membrane phospholipase.
Nature
|
