CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.670 | Formiminotransferase, C-terminal subdomain |
Domain Context
CATH Clusters
| Superfamily | Formiminotransferase, C-terminal subdomain |
| Functional Family | Formimidoyltransferase cyclodeaminase |
Enzyme Information
| 4.3.1.4 |
Formimidoyltetrahydrofolate cyclodeaminase.
based on mapping to UniProt P53603
5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH(3).
-!- In eukaroytes, occurs as a bifunctional enzyme that also has EC 2.1.2.5 activity.
|
| 2.1.2.5 |
Glutamate formimidoyltransferase.
based on mapping to UniProt P53603
5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate.
-!- In eukaryotes occurs as a bifunctional enzyme also having EC 4.3.1.4 activity. -!- Formerly EC 2.1.2.6.
|
UniProtKB Entries (1)
| P53603 |
FTCD_PIG
Sus scrofa
Formimidoyltransferase-cyclodeaminase
|
PDB Structure
| PDB | 1QD1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme.
Structure Fold.Des.
|
