CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.245 | Inosine-uridine Nucleoside N-ribohydrolase; Chain A |
|
3.90.245.10 | Ribonucleoside hydrolase-like |
Domain Context
CATH Clusters
| Superfamily | Ribonucleoside hydrolase-like |
| Functional Family | Pyrimidine-specific ribonucleoside hydrolase RihB |
Enzyme Information
| 3.2.2.8 |
Ribosylpyrimidine nucleosidase.
based on mapping to UniProt P33022
A pyrimidine nucleoside + H(2)O = D-ribose + a pyrimidine base.
-!- Also hydrolyzes purine D-ribonucleosides, more slowly. -!- 2'-, 3'- and 5'-deoxynucleosides are not substrates.
|
UniProtKB Entries (1)
| P33022 |
RIHB_ECOLI
Escherichia coli K-12
Pyrimidine-specific ribonucleoside hydrolase RihB
|
PDB Structure
| PDB | 1Q8F |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure to 1.7 a of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy.
STRUCTURE
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