CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.20 | Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 |
|
3.60.20.10 | Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 |
| Functional Family |
Enzyme Information
| 6.3.3.6 |
Carbapenam-3-carboxylate synthase.
based on mapping to UniProt Q9XB61
ATP + (2S,5S)-5-carboxymethylproline = AMP + diphosphate + (3S,5S)- carbapenam 3-carboxylate.
-!- The enzyme is involved in the biosynthesis of the carbapenem beta- lactam antibiotic (5R)-carbapen-2-em-3-carboxylate in the bacterium Pectobacterium carotovorum. -!- Formerly EC 6.3.1.16.
|
UniProtKB Entries (1)
| Q9XB61 |
CARA_PECCC
Pectobacterium carotovorum subsp. carotovorum
Carbapenam-3-carboxylate synthase
|
PDB Structure
| PDB | 1Q19 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of Carbapenam Synthetase (CarA)
J.Biol.Chem.
|