CATH Classification

Domain Context

CATH Clusters

Superfamily DNA-3-methyladenine glycosylase AlkA, N-terminal domain
Functional Family DNA-3-methyladenine glycosylase 2

Enzyme Information

3.2.2.21
DNA-3-methyladenine glycosylase II.
based on mapping to UniProt P04395
Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.

UniProtKB Entries (1)

P04395
3MG2_ECOLI
Escherichia coli K-12
DNA-3-methyladenine glycosylase 2

PDB Structure

PDB 1PVS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
3-methyladenine-DNA glycosylase II: the crystal structure of an AlkA-hypoxanthine complex suggests the possibility of product inhibition.
Teale, M., Symersky, J., DeLucas, L.
Bioconjug.Chem.
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