CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.600 | Farnesyl Diphosphate Synthase |
|
1.10.600.10 | Farnesyl Diphosphate Synthase |
Domain Context
CATH Clusters
| Superfamily | Farnesyl Diphosphate Synthase |
| Functional Family |
Enzyme Information
| 4.2.3.7 |
Pentalenene synthase.
based on mapping to UniProt Q55012
(2E,6E)-farnesyl diphosphate = pentalenene + diphosphate.
-!- Isolated from Streptomyces avermitilis. -!- The enzyme is involved in the biosynthesis of pentalenolactone and related antibiotics. -!- The 9si hydrogen of farnesyl diphosphate undergoes a 1,2-hydride shift where it becomes the 1-alpha hydrogen of pentalenene. -!- Formerly EC 4.6.1.5.
|
UniProtKB Entries (1)
| Q55012 |
PENA_STREX
Streptomyces exfoliatus
Pentalenene synthase
|
PDB Structure
| PDB | 1PS1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology.
Science
|
