CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.10 | Ribbon | |
2.10.210 | Cytochrome Bc1 Complex; Chain I | |
2.10.210.10 | Cytochrome Bc1 Complex; Chain I |
Domain Context
CATH Clusters
Superfamily | Cytochrome Bc1 Complex; Chain I |
Functional Family |
Enzyme Information
7.1.1.8 |
Quinol--cytochrome-c reductase.
based on mapping to UniProt P13272
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and c(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3). -!- Formerly EC 1.10.2.2.
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UniProtKB Entries (1)
P23004 |
QCR2_BOVIN
Bos taurus
Cytochrome b-c1 complex subunit 2, mitochondrial
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PDB Structure
PDB | 1PPJ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Binding of the Respiratory Chain Inhibitor Antimycin to the Mitochondrial bc(1) Complex: A New Crystal Structure Reveals an Altered Intramolecular Hydrogen-bonding Pattern.
J.Mol.Biol.
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