CATH Classification

Domain Context

CATH Clusters

Superfamily Laminin
Functional Family

Enzyme Information

3.4.21.22
Coagulation factor IXa.
based on mapping to UniProt P16293
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
-!- The proenzyme factor IX is activated by EC 3.4.21.27. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P16293
FA9_PIG
Sus scrofa
Coagulation factor IX

PDB Structure

PDB 1PFX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B.
Brandstetter, H., Bauer, M., Huber, R., Lollar, P., Bode, W.
Proc.Natl.Acad.Sci.USA
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