CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8X225
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (2)

Q8X225
DIM5_NEUCR
Neurospora crassa OR74A
Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5
P61830
H3_YEAST
Saccharomyces cerevisiae S288C
Histone H3

PDB Structure

PDB 1PEG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the product specificity of histone lysine methyltransferases
Zhang, X., Yang, Z., Khan, S.I., Horton, J.R., Tamaru, H., Selker, E.U., Cheng, X.
Mol.Cell
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